Title: Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants
|Authors:||G.Moro, I Minoli, M Mosca, G Boehm|
Journal of Pediatric Gastroenterology and Nutrition
Prebiotics found in human milk have been shown to stimulate selectively the growth of bifidobacteria and lactobacilli in the gut. This study focused on assessing the bifidogenic effect of a prebiotic oligosaccharide mixture of galacto-oligosaccharides and fructo-oligosaccharides in 90 term infants. The test infant formulas were supplemented with either 0.4 g/dL or with 0.8 g/dL oligosaccharides. In the control formula, maltodextrin was used as placebo. Results showed that supplementation of a term infant’s formula with a mixture of galacto- and fructooligosaccharides has a dose-dependent stimulating effect on the growth of bifidobacteria and lactobacilli in the intestine and results in softer stool with increasing dosage of supplementation.