Title: The Bifidogenic Effect Revisited—Ecology and Health Perspectives of Bifidobacterial Colonization in Early Life
|Authors:||Himanshu Kumar, Maria Carmen Collado, Harm Wopereis, Seppo Salminen, Jan Knol and Guus Roeselers|
This recently published review article focuses on “Bifidobacterium early-life type Bifidobacterium strains and their symbiotic relationship with humans and discusses examples of compromised microbiota development in which stimulating the abundance and activity of Bifidobacterium has demonstrated beneficial associations with health”.
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The gut is our biggest interface to the outside world and is home to the microbiota – a unique community of around 100 trillion bacteria. Vital for our health and wellbeing, gut bacteria have many health-promoting functions, including digestion and the development and functioning of our immune system.
Infant gut microbiota is important for a healthy growth as it influences gut maturation, immune, metabolic and brain development. Undesirable gut microbiota composition in early life is associated with disease risk later in life. Early-life events, such as mode of delivery (vaginal birth versus C-section), type of feeding, antibiotic use, and others influence the shaping the infant gut microbiota and can lead to a compromised microbiome.
Bifidobacterium is often a dominant species in the microbiota of healthy infants, whereas compromised microbiota often sees decreased numbers of Bifidobacterium species.
Various microbiome modulation strategies such as probiotic, prebiotics, synbiotics and postbiotics have been developed to help restore the microbiota development by re-introducing bifodobacteria.
More recently, bifidobacteria-based probiotics and synbiotics are also being investigated in adults and aging subjects and hence could contribute to overall health.
Find out more about the central role of the gut on our website: https://www.nutriciaresearch.com/gut-and-microbiology/the-central-role-of-the-gut/