Title: Effect of Synbiotics on the Gut Microbiota of Caesarean Delivered Infants: A Randomized, Double-Blind, Multicenter Study
|Authors:||Chua MC, Ben-Amor K, Lay C, Neo AGE, Chiang WC, Rao R, Chew C, Chaithongwongwatthana S, Khemapech N, Knol J, Chongsrisawat V|
Journal of Pediatric Gastroenterology and Nutrition
Caesarean birth has been associated with increased risk of immune and metabolic diseases later in life, likely due to the altered gut microbiota.
This study finding confirms that babies born by C-section have a reduced number of bifidobacteria (beneficial bacteria) in the first days of life. Supplementing the infant formula with our synbiotics (short-chain galacto-oligosaccharides [scGOS], long-chain fructo-oligosaccharides [lcFOS] and Bifidobacterium breve M-16V) compensates the bifidobacteria colonisation in C-section delivered babies. The synbiotic also modulates the gut physiological conditions (produces acetate and lowers pH), which were described as an indicator of gut health.
This further strengthens the clinical evidence of our synbiotics concept.
Download the study summary and key results.